4 papers
Persistent Manifold Learning of Protein Properties
Xingjian Xu, Zhe Su, Guo-Wei Wei +1
Predicting how tightly two biomolecules bind remains a major challenge, in part because different interaction classes present dissimilar interfaces, from compact metal-coordinated…
The finite expression method for turbulent dynamics with high-order moment recovery
Xingjian Xu, Di Qi, Chunmei Wang
Turbulent dynamical systems are characterized by nonlinear interactions and stochastic effects that generate coupled statistical quantities, such as non-zero higher-order moments,…
Identifying Unknown Stochastic Dynamics via Finite expression methods
Senwei Liang, Chunmei Wang, Xingjian Xu
Modeling stochastic differential equations (SDEs) is crucial for understanding complex dynamical systems in various scientific fields. Recent methods often employ neural network-ba…
PLD-Tree: Persistent Laplacian Decision Tree for Protein-Protein Binding Free Energy Prediction
Xingjian Xu, Jiahui Chen, Chunmei Wang
Recent advances in topology-based modeling have accelerated progress in physical modeling and molecular studies, including applications to protein-ligand binding affinity. In this…