5 papers
Life-Code: Central Dogma Modeling with Multi-Omics Sequence Unification
Zicheng Liu, Siyuan Li, Zhiyuan Chen +6
The interactions between DNA, RNA, and proteins are fundamental to biological processes, as illustrated by the central dogma of molecular biology. Although modern biological pre-tr…
MergeDNA: Context-aware Genome Modeling with Dynamic Tokenization through Token Merging
Siyuan Li, Kai Yu, Anna Wang +7
Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit.…
A Survey on Mixup Augmentations and Beyond
Xin Jin, Hongyu Zhu, Siyuan Li +6
As Deep Neural Networks have achieved thrilling breakthroughs in the past decade, data augmentations have garnered increasing attention as regularization techniques when massive la…
MergeVQ: A Unified Framework for Visual Generation and Representation with Disentangled Token Merging and Quantization
Siyuan Li, Luyuan Zhang, Zedong Wang +8
Masked Image Modeling (MIM) with Vector Quantization (VQ) has achieved great success in both self-supervised pre-training and image generation. However, most existing methods strug…
Artificial Intelligence for Central Dogma-Centric Multi-Omics: Challenges and Breakthroughs
Lei Xin, Caiyun Huang, Hao Li +8
With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being appli…