457 citations · 459 across the 4 of their papers we have counts for
4 papers
A natural upper bound to the accuracy of predicting protein stability changes upon mutations
Ludovica Montanucci, Pier Luigi Martelli, Nir Ben-Tal +1
Accurate prediction of protein stability changes upon single-site variations (DDG) is important for protein design, as well as our understanding of the mechanism of genetic disease…
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Yuxiang Jiang, Tal Ronnen Oron, Wyatt T Clark +144
Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations i…
In silico evidence of the relationship between miRNAs and siRNAs
Ludovica Montanucci, Piero Fariselli, Pier Luigi Martelli +2
Both short interfering RNAs (siRNAs) and microRNAs (miRNAs) mediate the repression of specific sequences of mRNA through the RNA interference pathway. In the last years several exp…
The posterior-Viterbi: a new decoding algorithm for hidden Markov models
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
Background: Hidden Markov models (HMM) are powerful machine learning tools successfully applied to problems of computational Molecular Biology. In a predictive task, the HMM is end…