activity
19992020
most citedDuplication-divergence model of protein interaction network

179 citations · 877 across the 27 of their papers we have counts for

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6 papers · 1 filter

q-bio.MN2007★ 83 cited

Propagation of large concentration changes in reversible protein binding networks

Sergei Maslov, I. Ispolatov

We study how the dynamic equilibrium of the reversible protein-protein binding network in yeast Saccharomyces cerevisiae responds to large changes in abundances of individual prote…

q-bio.MN2007

Detection of the dominant direction of information flow in densely interconnected regulatory networks

I. Ispolatov, Sergei Maslov

Finding the dominant direction of flow of information in densely interconnected regulatory or signaling networks is required in many applications in computational biology and neuro…

q-bio.MN2006★ 28 cited

Propagation of fluctuations in interaction networks governed by the law of mass action

Sergei Maslov, Kim Sneppen, Iaroslav Ispolatov

Using an example of physical interactions between proteins, we study how perturbations propagate in interconnected networks whose equilibrium state is governed by the law of mass a…

q-bio.MN2005★ 14 cited

Finding mesoscopic communities in sparse networks

I. Ispolatov, I. Mazo, A. Yuryev

We suggest a fast method to find possibly overlapping network communities of a desired size and link density. Our method is a natural generalization of the finite- superparamegn…

q-bio.MN2005★ 34 cited

Cliques and duplication-divergence network growth

I. Ispolatov, P. L. Krapivsky, I. Mazo +1

A population of complete subgraphs or cliques in a network evolving via duplication-divergence is considered. We find that a number of cliques of each size scales linearly with the…

q-bio.MN2004★ 179 cited

Duplication-divergence model of protein interaction network

I. Ispolatov, P. L. Krapivsky, A. Yuryev

We show that the protein-protein interaction networks can be surprisingly well described by a very simple evolution model of duplication and divergence. The model exhibits a remark…