6 papers
Crowding competes with trapping to enhance interfacial diffusion
Mislav Cvitković, Dipanwita Ghanti, Niklas Raake +1
Diffusion in the crowded environments of the biological membranes or materials interfaces often involves intermittent binding to surface proteins or defects. To account for this si…
Fidelity of bacterial translation initiation: a stochastic kinetic model
Dipanwita Ghanti, Kelvin Caban, Joachim Frank +2
During the initiation stage of protein synthesis, a ribosomal initiation complex (IC) is assembled on a messenger RNA (mRNA) template. In bacteria, the speed and accuracy of this a…
Strength and stability of active ligand-receptor bonds: a microtubule attached to a wall by molecular motor tethers
Dipanwita Ghanti, Raymond W. Friddle, Debashish Chowdhury
We develop a stochastic kinetic model of a pre-formed attachment of a mictrotuble (MT) with a cell cortex, in which the MT is tethered to the cell by a group of active motor protei…
Molecular force spectroscopy of kinetochore-microtubule attachment {\it in silico}: Mechanical signatures of an unusual catch bond and collective effects
Dipanwita Ghanti, Shubhadeep Patra, Debashish Chowdhury
Measurement of the life time of attachments formed by a single microtubule (MT) with a single kinetochore (kt) {\it in-vitro} under force-clamp conditions had earlier revealed a ca…
A Multispecies Exclusion Model Inspired By Transcriptional Interference
Soumendu Ghosh, Tripti Bameta, Dipanwita Ghanti +1
We introduce exclusion models of two distinguishable species of hard rods with their distinct sites of entry and exit under open boundary conditions. In the first model both specie…
Mixed molecular motor traffic on nucleic acid tracks: models of transcriptional interference and regulation of gene expression
Tripti Bameta, Debashish Chowdhury, Dipanwita Ghanti +1
RNA polymerase (RNAP) is molecular machine that polymerizes a RNA molecule, a linear heteropolymer, using a single stranded DNA (ssDNA) as the corresponding template; the sequence…