5 papers
Order and shape dependence of mechanical relaxation in proliferating active matter
Jonas Isensee, Lukas Hupe, Philip Bittihn
Collective dynamics in proliferating anisotropic particle systems arise from an interplay between growth, division, and mechanical interactions, often mediated by particle shape. I…
Prediction and control of geometry-induced nematic order in growing multicellular systems
Lukas Hupe, Jonas Isensee, Ramin Golestanian +1
In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientat…
Phase separation in a mixture of proliferating and motile active matter
Lukas Hupe, Joanna M. Materska, David Zwicker +3
Proliferation and motility are ubiquitous drivers of activity in biological systems. Here, we study a dense binary mixture of motile and proliferating particles with exclusively re…
Motility-induced mixing transition in exponentially growing multicellular spheroids
Torben Sunkel, Lukas Hupe, Philip Bittihn
Growth drives cellular dynamics in dense aggregates including bacterial colonies, developing tissues, and tumors. We investigate the underlying physical principles emerging from th…
Isovolumetric dividing active matter
Samantha R. Lish, Lukas Hupe, Ramin Golestanian +1
We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confin…