35 citations · 47 across the 9 of their papers we have counts for
10 papers
Dynamical noisy canalization in morphogenesis: lessons from Hydra regeneration
Oded Agam, Erez Braun
Developmental robustness is framed as progress through a fixed Waddington-type landscape. We argue that in morphogenesis this landscape evolves through coupled bio-signaling, mecha…
Rupture-Repair Cycles in Regenerating Hydra Tissues
Oded Agam, Erez Braun
Destructive mechanical breakdowns and fractures are ubiquitous events in driven physical matter; living tissues, by contrast, can rupture repeatedly while restoring integrity. Here…
The Dual Nature of Body-Axis Formation in Hydra Regeneration: Polarity-Morphology Concurrency
Oded Agam, Erez Braun
The formation of a body-axis is central to animal development and involves both polarity and morphology. While polarity is traditionally associated with biochemical patterning, the…
Fluctuation-Driven Morphological Patterning: A Novel Approach to Morphogenesis
Oded Agam, Erez Braun
Recent experimental investigations into Hydra regeneration revealed a remarkable phenomenon: the morphological transformation of a tissue fragment from the incipient spherical conf…
Universal Calcium fluctuations in Hydra morphogenesis
Oded Agam, Erez Braun
Understanding how the collective physical processes drive robust morphological transitions in animal development requires the characterization of the relevant fields underlying mor…
Hydra morphogenesis as phase-transition dynamics
Oded Agam, Erez Braun
We utilize whole-body Hydra regeneration from a small tissue segment to develop a physics framework for animal morphogenesis. Introducing experimental controls over this process, a…
Calcium fluctuations drive morphological patterning at the onset of Hydra morphogenesis
Erez Braun
Morphogenesis in animal development involves significant morphological transitions leading to the emerging body plan of a mature animal. Understanding how the collective physical p…
Electric-induced reversal of morphogenesis in Hydra
Erez Braun, Hillel Ori
Morphogenesis involves the dynamic interplay of biochemical, mechanical and electrical processes. Here we ask: to what extent can the course of morphogenesis be modulated and contr…
Single-cell protein dynamics reproduce universal fluctuations in cell populations
Naama Brenner, Erez Braun, Anna Yoney +3
Protein variability in single cells has been studied extensively in populations, but little is known about temporal protein fluctuations in a single cell over extended times. We pr…
Universal protein fluctuations in populations of microorganisms
Hanna Salman, Naama Brenner, Chih-kuan Tung +5
The copy number of any protein fluctuates among cells in a population; characterizing and understanding these fluctuations is a fundamental problem in biophysics. We show here that…