activity
20142026
most citedGeneralizing causal inferences from individuals in randomized trials to all trial-eligible individuals

164 citations · 526 across the 53 of their papers we have counts for

collaborators

58 papers

stat.ME2026

What does two-sample Mendelian randomization estimate when the exposure-outcome relationship is nonlinear?

Eric J. Tchetgen Tchetgen

Two-sample Mendelian randomization with summary statistics has become a popular MR design in Epidemiology. Its ratio estimate has an average causal effect interpretation only under…

stat.ME2026

Regression-Based Proximal Reconciliation of Conflicting Trials with Unmeasured Effect Modifiers

Daniel A Xu, Eric J Tchetgen Tchetgen, Enrique F Schisterman +2

Randomized controlled trials with similar protocols may yield conflicting findings when the distribution of relevant effect modifiers differs across study populations. Yet no forma…

stat.ME2026

How should we select test-negative controls? A causal perspective in the era of multiplex respiratory testing

Christopher B. Boyer, Kendrick Qijun Li, Xu Shi +2

The test-negative design (TND) is widely used to estimate vaccine effectiveness (VE) for respiratory pathogens by comparing vaccination odds among test-positive cases versus test-n…

stat.ME2026

A General Exposure-Mapping-Agnostic Framework for Causal Inference under Interference

Yihui He, Eric J. Tchetgen Tchetgen

We develop a general framework for design-based causal inference under interference in cluster experiments conducted via two-stage randomization on a network of interconnected unit…

stat.ME2026

Exploiting independence constraints for efficient estimation of bounds on causal effects in the presence of unmeasured confounding

Ting-Hsuan Chang, Caleb H. Miles, Ilya Shpitser +2

Causal graphs may inform covariate adjustment for estimating causal effects and improve estimation efficiency by exploiting the graphical structure. In many applications, however,…

stat.ME2026

The Multiplicative Quasi-Instrumental Variable Model

Jiewen Liu, Chan Park, David Richardson +1

We introduce the Multiplicative Quasi-Instrumental Variable (MQIV) model, a framework for causal inference with unmeasured confounding that leverages an instrument that may be impe…

stat.ME2025

The Multiplicative Instrumental Variable Model

Jiewen Liu, Chan Park, Yonghoon Lee +4

The instrumental variable (IV) design is a common approach to address hidden confounding bias. For validity, an IV must impact the outcome only through its association with the tre…

stat.ME2025

Doubly Robust and Efficient Calibration of Prediction Sets for Right-Censored Time-to-Event Outcomes

Rebecca Farina, Eric J. Tchetgen Tchetgen, Arun Kumar Kuchibhotla

Our objective is to construct well-calibrated prediction sets for a time-to-event outcome subject to right-censoring with guaranteed coverage. Inspired by modern conformal inferenc…

stat.ME2024

Proximal Causal Inference for Conditional Separable Effects

Chan Park, Mats Stensrud, Eric Tchetgen Tchetgen

Scientists regularly pose questions about treatment effects on outcomes conditional on a post-treatment event. However, causal inference in such settings requires care, even in per…

stat.ME2024

Regression-Based Proximal Causal Inference

Jiewen Liu, Chan Park, Kendrick Li +1

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the pre…

stat.ME2023

Proximal Causal Inference for Synthetic Control with Surrogates

Jizhou Liu, Eric J. Tchetgen Tchetgen, Carlos Varjão

The synthetic control method (SCM) has become a popular tool for estimating causal effects in policy evaluation, where a single treated unit is observed, and a heterogeneous set of…

stat.ME2023

Single Proxy Synthetic Control

Chan Park, Eric Tchetgen Tchetgen

Synthetic control methods are widely used to estimate the treatment effect on a single treated unit in time-series settings. A common approach to estimate synthetic control weights…

stat.ME2023

Single Proxy Control

Chan Park, David Richardson, Eric Tchetgen Tchetgen

Negative control variables are sometimes used in non-experimental studies to detect the presence of confounding by hidden factors. A negative control outcome (NCO) is an outcome th…

stat.ME2023★ 2 cited

Universal Difference-in-Differences for Causal Inference in Epidemiology

Eric Tchetgen Tchetgen, Chan Park, David Richardson

Difference-in-differences is undoubtedly one of the most widely used methods for evaluating the causal effect of an intervention in observational (i.e., nonrandomized) settings. Th…

stat.ME2022

Doubly Robust Proximal Synthetic Controls

Hongxiang Qiu, Xu Shi, Wang Miao +2

To infer the treatment effect for a single treated unit using panel data, synthetic control methods construct a linear combination of control units' outcomes that mimics the treate…

stat.ME2022★ 1 cited

Using Instruments for Selection to Adjust for Selection Bias in Mendelian Randomization

Apostolos Gkatzionis, Eric J. Tchetgen Tchetgen, Jon Heron +2

Selection bias is a common concern in epidemiologic studies. In the literature, selection bias is often viewed as a missing data problem. Popular approaches to adjust for bias due…

stat.ME2022

A self-censoring model for multivariate nonignorable nonmonotone missing data

Yilin Li, Wang Miao, Ilya Shpitser +1

We introduce a self-censoring model for multivariate nonignorable nonmonotone missing data, where the missingness process of each outcome is affected by its own value and is associ…

stat.ME2022

Using negative controls to identify causal effects with invalid instrumental variables

Oliver Dukes, David B. Richardson, Zachary Shahn +2

Many proposals for the identification of causal effects require an instrumental variable that satisfies strong, untestable unconfoundedness and exclusion restriction assumptions. I…

stat.ME2022★ 1 cited

Prediction Sets Adaptive to Unknown Covariate Shift

Hongxiang Qiu, Edgar Dobriban, Eric Tchetgen Tchetgen

Predicting sets of outcomes -- instead of unique outcomes -- is a promising solution to uncertainty quantification in statistical learning. Despite a rich literature on constructin…

stat.AP2021★ 1 cited

Improving Fairness in Criminal Justice Algorithmic Risk Assessments Using Optimal Transport and Conformal Prediction Sets

Richard A. Berk, Arun Kumar Kuchibhotla, Eric Tchetgen Tchetgen

In the United States and elsewhere, risk assessment algorithms are being used to help inform criminal justice decision-makers. A common intent is to forecast an offender's ``future…

math.ST2021★ 4 cited

Nonparametric inference about mean functionals of nonignorable nonresponse data without identifying the joint distribution

Wei Li, Wang Miao, Eric Tchetgen Tchetgen

We consider identification and inference about mean functionals of observed covariates and an outcome variable subject to nonignorable missingness. By leveraging a shadow variable,…

stat.ME2021★ 3 cited

Proximal mediation analysis

Oliver Dukes, Ilya Shpitser, Eric J. Tchetgen Tchetgen

A common concern when trying to draw causal inferences from observational data is that the measured covariates are insufficiently rich to account for all sources of confounding. In…

stat.ME2021★ 6 cited

Proximal Causal Inference for Complex Longitudinal Studies

Andrew Ying, Wang Miao, Xu Shi +1

A standard assumption for causal inference about the joint effects of time-varying treatment is that one has measured sufficient covariates to ensure that within covariate strata,…

cs.LG2021★ 2 cited

End-to-End Balancing for Causal Continuous Treatment-Effect Estimation

Mohammad Taha Bahadori, Eric Tchetgen Tchetgen, David E. Heckerman

We study the problem of observational causal inference with continuous treatments in the framework of inverse propensity-score weighting. To obtain stable weights, we design a new…