16 citations · 18 across the 3 of their papers we have counts for
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q-bio.QM2016★ 2 cited
A Weighted Exact Test for Mutually Exclusive Mutations in Cancer
Mark D. M. Leiserson, Matthew A. Reyna, Benjamin J. Raphael
The somatic mutations in the pathways that drive cancer development tend to be mutually exclusive across tumors, providing a signal for distinguishing driver mutations from a large…
q-bio.QM2015
CoMEt: A Statistical Approach to Identify Combinations of Mutually Exclusive Alterations in Cancer
Mark D. M. Leiserson, Hsin-Ta Wu, Fabio Vandin +1
Cancer is a heterogeneous disease with different combinations of genetic and epigenetic alterations driving the development of cancer in different individuals. While these alterati…