activity
20152025
most citedBifurcation analysis and potential landscape of the p53-Mdm2 oscillator regulated by the co-activator PDCD5

1 citations · 1 across the 2 of their papers we have counts for

collaborators

6 papers

math.RT2025

Half-Diagrams in Partition Algebras: A Geometric Perspective on Multiplicities

Pei Wang, Changjing Zhuge

This paper studies the restriction multiplicities of half-diagram modules for the partition algebra and their geometric interpretations. By specializing the Bowman-De Visscher-Orel…

q-bio.TO2025

A tumor-immune model of chronic myeloid leukemia with optimal immunotherapeutic protocols

Haifeng Zhang, Changjing Zhuge, Jinzhi Lei

The interactions between tumor cells and the immune system play a crucial role in cancer evolution. In this study, we explore how these interactions influence cancer progression by…

q-bio.QM2025

How cancer emerges: Data-driven universal insights into tumorigenesis via hallmark networks

Jiahe Wang, Yan Wu, Yuke Hou +4

Cancer is a complex disease driven by dynamic regulatory shifts that cannot be fully captured by individual molecular profiling. We employ a data-driven approach to construct a coa…

q-bio.PE2020

Epidemic analysis of COVID-19 in China by dynamical modeling

Liangrong Peng, Wuyue Yang, Dongyan Zhang +2

The outbreak of novel coronavirus-caused pneumonia (COVID-19) in Wuhan has attracted worldwide attention. Here, we propose a generalized SEIR model to analyze this epidemic. Based…

q-bio.MN2015

PDCD5 interacts with p53 and functions as a regulator of p53 dynamics in the DNA damage response

Changjing Zhuge, Xiaojuan Sun, Yingyu Chen +1

The tumor suppressor p53 plays a central role in cell fate decisions after DNA damage. Programmed Cell Death 5 (PDCD5) is known to interact with the p53 pathway to promote cell apo…

q-bio.MN20151 cited

Bifurcation analysis and potential landscape of the p53-Mdm2 oscillator regulated by the co-activator PDCD5

Yuanhong Bi, Zhuoqin Yang, Changjing Zhuge +1

Dynamics of p53 is known to play important roles in the regulation of cell fate decisions in response to various stresses, and PDCD5 functions as a co-activator of p53 to modulate…