25 citations · 32 across the 6 of their papers we have counts for
6 papers
Scaling up machine learning-based chemical plant simulation: A method for fine-tuning a model to induce stable fixed points
Malte Esders, Gimmy Alex Fernandez Ramirez, Michael Gastegger +1
Idealized first-principles models of chemical plants can be inaccurate. An alternative is to fit a Machine Learning (ML) model directly to plant sensor data. We use a structured ap…
Critical Transitions in Intensive Care Units: A Sepsis Case Study
Pejman F. Ghalati, Satya S. Samal, Jayesh S. Bhat +3
The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights…
Geometric analysis of pathways dynamics: application to versatility of TGF-β receptors
Satya Swarup Samal, Aurélien Naldi, Dima Grigoriev +3
We propose a new geometric approach to describe the qualitative dynamics of chemical reactions networks. By this method we identify metastable regimes, defined as low dimensional r…
A geometric method for model reduction of biochemical networks with polynomial rate functions
Satya Swarup Samal, Dima Grigoriev, Holger Fröhlich +2
Model reduction of biochemical networks relies on the knowledge of slow and fast variables. We provide a geometric method, based on the Newton polytope, to identify slow variables…
Analysis of Reaction Network Systems Using Tropical Geometry
Satya Swarup Samal, Dima Grigoriev, Holger Fröhlich +1
We discuss a novel analysis method for reaction network systems with polynomial or rational rate functions. This method is based on computing tropical equilibrations defined by the…
Symbolic dynamics of biochemical pathways as finite states machines
Ovidiu Radulescu, Satya Swarup Samal, Aurélien Naldi +2
We discuss the symbolic dynamics of biochemical networks with separate timescales. We show that symbolic dynamics of monomolecular reaction networks with separated rate constants c…