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physics.bio-ph2015★ 1 cited
Pitfalls in the quantitative analysis of random walks and the mapping of single-molecule dynamics at the cellular scale
Jean-Baptiste Masson, Maxime Dahan, Antoine Triller
In recent years Bayesian Inference has become an efficient tool to analyse single molecule trajectories. Recently, high density single molecule tagging, Langevin Equation modelling…
physics.bio-ph2015★ 107 cited
Mapping the energy and diffusion landscapes of membrane proteins at the cell surface using high-density single-molecule imaging and Bayesian inference: application to the multi-scale dynamics of glycine receptors in the neuronal membrane
Jean-Baptiste Masson, Patrice Dionne, Charlotte Salvatico +4
Protein mobility is conventionally analyzed in terms of an effective diffusion. Yet, this description often fails to properly distinguish and evaluate the physical parameters (such…