320 citations · 449 across the 5 of their papers we have counts for
Showing 2015Show all
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q-bio.MN2015★ 38 cited
mRNA-miRNA Reciprocal Regulation Enabled Bistable Switch Directs Cell Fate Decision
Xiao-Jun Tian, Hang Zhang, Jingyu Zhang +1
miRNAs serve as crucial post-transcriptional regulators in various essential cell fate decision. However, the contribution of the mRNA-miRNA mutual regulation to bistability is not…
q-bio.MN2015★ 33 cited
Achieving Diverse and Monoallelic Olfactory Receptor Selection Through Dual-Objective Optimization Design
Xiao-Jun Tian, Hang Zhang, Jens Sannerud +1
Multiple-objective optimization is common in biological systems. In the mammalian olfactory system, each sensory neuron stochastically expresses only one out of up to thousands of…
q-bio.MN2015
Computational modeling to elucidate molecular mechanisms of epigenetic memory
Jianhua Xing, Jin Yu, Hang Zhang +1
How do mammalian cells that share the same genome exist in notably distinct phenotypes, exhibiting differences in morphology, gene expression patterns, and epigenetic chromatin sta…