12 papers
Quantitative Characterization of Brain Tissue Alterations in Brain Cancer Using Fractal, Multifractal, and IPR Metrics
Mousa Alrubayan, Santanu Maity, Prabhakar Pradhan
We studied the structural alterations between healthy and diseased brain tissues using a multiparametric framework combining fractal analysis, fractal functional transformation, mu…
Alterations of brain tissue structural complexity and disorder in Alzheimer's disease (AD): Fractal, multifractal, fractal transformation, and disorder strength analyses
Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1
Alzheimer's disease (AD) is characterized by progressive microstructural deterioration in brain tissue, yet conventional imaging and histopathology often lack the sensitivity neede…
Alterations of brain tissue structural complexity and disorder in Parkinson disease (PD): Fractal, multifractal, fractal transformation, and disorder strength analyses
Santanu Maity, Mousa Alrubayan, Mohammad Moshahid Khan +1
Parkinson disease (PD) is marked by progressive neurodegeneration, yet early and subtle structural alterations in brain tissue remain difficult to detect with conventional imaging…
Comprehensive Multimodal and Multiscale Analysis of Alzheimer Disease in 5xFAD Mice: Optical Spectroscopies, TEM, Neuropathological, and Behavioral Investigations
Dhruvil Solanki, Ishmael Apachigawo, Sazzad Khan +8
Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms…
Decoding Breast Cancer in X-ray Mammograms: A Multi-Parameter Approach Using Fractals, Multifractals, and Structural Disorder Analysis
Santanu Maity, Mousa Alrubayan, Prabhakar Pradhan
We explored the fractal and multifractal characteristics of breast mammogram micrographs to identify quantitative biomarkers associated with breast cancer progression. In addition…
Evaluation and optimization of deep learning models for enhanced detection of brain cancer using transmission optical microscopy of thin brain tissue samples
Mohnish Sao, Mousa Alrubayan, Prabhakar Pradhan
Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive a…