4 papers
A mathematical model for smooth muscle cell phenotype switching in atherosclerotic plaque
Joseph P. Ndenda, Michael G. Watson, Ashish Misra +1
Smooth muscle cells (SMCs) play a fundamental role in the development of atherosclerotic plaques. They ingest lipids in a similar way to monocyte-derived macrophages (MDMs) in the…
Assessing Honey Bee Colony Health Using Temperature Time Series
Karina Arias-Calluari, Theotime Colin, Tanya Latty +2
Honey bees face an increasing number of stressors that disrupt the natural behaviour of colonies and, in extreme cases, can lead to their collapse. Quantifying the status and resil…
A spatially resolved and lipid-structured model for macrophage populations in early human atherosclerotic lesions
Keith L. Chambers, Mary R. Myerscough, Michael G. Watson +1
Atherosclerosis is a chronic inflammatory disease of the artery wall. The early stages of atherosclerosis are driven by interactions between lipids and monocyte-derived-macrophages…
Blood lipoproteins shape the phenotype and lipid content of early atherosclerotic lesion macrophages: a dual-structured mathematical model
Keith L Chambers, Mary R Myerscough, Michael G Watson +1
Macrophages in atherosclerotic lesions exhibit a spectrum of behaviours or phenotypes. The phenotypic distribution of monocyte-derived macrophages (MDMs), its correlation with MDM…