17.8k citations · 40.3k across the 19 of their papers we have counts for
3 papers · 1 filter
Twelve years of SAMtools and BCFtools
Petr Danecek, James K. Bonfield, Jennifer Liddle +8
Background SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. Findings The first version appeared online twelve years ago…
Haplotype-resolved de novo assembly with phased assembly graphs
Haoyu Cheng, Gregory T Concepcion, Xiaowen Feng +2
Haplotype-resolved de novo assembly is the ultimate solution to the study of sequence variations in a genome. However, existing algorithms either collapse heterozygous alleles into…
The design and construction of reference pangenome graphs
Heng Li, Xiaowen Feng, Chong Chu
The recent advances in sequencing technologies enables the assembly of individual genomes to the reference quality. How to integrate multiple genomes from the same species and to m…