48 citations · 106 across the 14 of their papers we have counts for
3 papers · 1 filter
Modeling ionic flow between small targets: insights from diffusion and electro-diffusion theory
Frédéric Paquin-Lefebvre, David Holcman
The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltag…
How large should be the redundant numbers of copy to make a rare event probable
Fred Paquin-Lefebvre, Suney Toste, David Holcman
The redundancy principle provides the framework to study how rare events are made possible with probability 1 in accelerated time, by making many copies of similar random searchers…
Encounter dynamics of a small target by a polymer diffusing in a confined domain
A. Amitai, Carlo Amoruso, Avi Ziskind +1
We study the first passage time for a polymer, that we call the narrow encounter time (NETP), to reach a small target located on the surface of a microdomain. The polymer is modele…