4 papers
Learning What Matters: Steering Diffusion via Spectrally Anisotropic Forward Noise
Luca Scimeca, Thomas Jiralerspong, Berton Earnshaw +2
Diffusion Probabilistic Models (DPMs) have achieved strong generative performance, yet their inductive biases remain largely implicit. In this work, we aim to build inductive biase…
Virtual Cells: Predict, Explain, Discover
Emmanuel Noutahi, Jason Hartford, Prudencio Tossou +12
Drug discovery is fundamentally a process of inferring the effects of treatments on patients, and would therefore benefit immensely from computational models that can reliably simu…
TxPert: Leveraging Biochemical Relationships for Out-of-Distribution Transcriptomic Perturbation Prediction
Frederik Wenkel, Wilson Tu, Cassandra Masschelein +12
Accurately predicting cellular responses to genetic perturbations is essential for understanding disease mechanisms and designing effective therapies. Yet exhaustively exploring th…
Shaping Inductive Bias in Diffusion Models through Frequency-Based Noise Control
Thomas Jiralerspong, Berton Earnshaw, Jason Hartford +2
Diffusion Probabilistic Models (DPMs) are powerful generative models that have achieved unparalleled success in a number of generative tasks. In this work, we aim to build inductiv…