169 citations · 291 across the 4 of their papers we have counts for
4 papers
Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations
Aron R. Perez-Lopez, Kristof Z. Szalay, Denes Turei +4
Network-based methods are playing an increasingly important role in drug design. Our main question in this paper was whether the efficiency of drug target proteins to spread pertur…
ComPPI, a cellular compartment-specific database for protein-protein interaction network analysis
Daniel V. Veres, David M. Gyurko, Benedek Thaler +4
Here we present ComPPI, a cellular compartment specific database of proteins and their interactions enabling an extensive, compartmentalized protein-protein interaction network ana…
Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism
Peter Csermely, Janos Hodsagi, Tamas Korcsmaros +7
Cancer is increasingly perceived as a systems-level, network phenomenon. The major trend of malignant transformation can be described as a two-phase process, where an initial incre…
Perturbation centrality and Turbine: a novel centrality measure obtained using a versatile network dynamics tool
Kristof Z. Szalay, Peter Csermely
Analysis of network dynamics became a focal point to understand and predict changes of complex systems. Here we introduce Turbine, a generic framework enabling fast simulation of a…