37 citations · 106 across the 4 of their papers we have counts for
4 papers
RNAiFold2T: Constraint Programming design of thermo-IRES switches
Juan Antonio Garcia-Martin, Ivan Dotu, Javier Fernandez-Chamorro +4
Motivation: RNA thermometers (RNATs) are cis-regulatory ele- ments that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shoc…
RNA thermodynamic structural entropy
Juan Antonio Garcia-Martin, Peter Clote
Conformational entropy for atomic-level, three dimensional biomolecules is known experimentally to play an important role in protein-ligand discrimination, yet reliable computation…
RNAiFold 2.0: A web server and software to design custom and Rfam-based RNA molecules
Juan Antonio Garcia-Martin, Ivan Dotu, Peter Clote
Several algorithms for RNA inverse folding have been used to design synthetic riboswitches, ribozymes and thermoswitches, whose activity has been experimentally validated. The RNAi…
Complete RNA inverse folding: computational design of functional hammerhead ribozymes
Ivan Dotu, Juan Antonio Garcia-Martin, Betty L. Slinger +3
Nanotechnology and synthetic biology currently constitute one of the most innovative, interdisciplinary fields of research, poised to radically transform society in the 21st centur…