1 citations · 1 across the 3 of their papers we have counts for
3 papers
q-bio.GN2015
BACOM2: a Java tool for detecting normal cell contamination of copy number in heterogeneous tumor
Yi Fu, Jun Ruan, Guoqiang Yu +6
We develop a cross-platform open-source Java application (BACOM2) with graphic user interface (GUI), and users also can use a XML file to set the parameters of algorithm model, fil…
stat.ML2013★ 1 cited
A feasible roadmap for unsupervised deconvolution of two-source mixed gene expressions
Niya Wang, Eric P. Hoffman, Robert Clarke +7
Tissue heterogeneity is a major confounding factor in studying individual populations that cannot be resolved directly by global profiling. Experimental solutions to mitigate tissu…
q-bio.GN2013
BACOM 2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor
Yi Fu, Guoqiang Yu, Douglas A. Levine +5
BACOM is a statistically principled and unsupervised method that detects copy number deletion types (homozygous versus heterozygous), estimates normal cell fraction, and recovers c…