423 citations · 1k across the 18 of their papers we have counts for
18 papers
Stochastic Kinetic Study of Protein Aggregation and Molecular Crowding Effects of Ab40 and Ab42
John Bridstrup, Jian-Min Yuan, John S. Schreck
Two isoforms of beta amyloid peptides, Ab40 and Ab42, differ from each other only in the last two amino acids, IA, at the end of Ab42. They, however, differ significantly in their…
Neural network processing of holographic images
John S. Schreck, Gabrielle Gantos, Matthew Hayman +2
HOLODEC, an airborne cloud particle imager, captures holographic images of a fixed volume of cloud to characterize the types and sizes of cloud particles, such as water droplets an…
Free-energy landscapes of DNA and its assemblies: Perspectives from coarse-grained modelling
Jonathan P. K. Doye, Ard A. Louis, John S. Schreck +5
This chapter will provide an overview of how characterizing free-energy landscapes can provide insights into the biophysical properties of DNA, as well as into the behaviour of the…
Characterizing the free-energy landscapes of DNA origamis
Chak Kui Wong, Chuyan Tang, John S. Schreck +1
We show how coarse-grained modelling combined with umbrella sampling using distance-based order parameters can be applied to compute the free-energy landscapes associated with mech…
Stochastic kinetic treatment of protein aggregation and the effects of macromolecular crowding
John Bridstrup, John S Schreck, Jesse L Jorgenson +1
Investigation of protein self-assembly processes is important for the understanding of the growth processes of functional proteins as well as disease-causing amyloids. Inside cells…
The oxDNA coarse-grained model as a tool to simulate DNA origami
Jonathan P. K. Doye, Hannah Fowler, Domen Prešern +12
This chapter introduces how to run molecular dynamics simulations for DNA origami using the oxDNA coarse-grained model.