78 citations · 223 across the 5 of their papers we have counts for
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q-bio.MN2015★ 78 cited
Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer
Sriganesh Srihari, Jitin Singla, Limsoon Wong +1
Background: Synthetic lethality (SL) refers to the genetic interaction between two or more genes where only their co-alteration (e.g. by mutations, amplifications or deletions) res…
q-bio.MN2015★ 75 cited
Methods for protein complex prediction and their contributions towards understanding the organization, function and dynamics of complexes
Sriganesh Srihari, Chern Han Yong, Ashwini Patil +1
Complexes of physically interacting proteins constitute fundamental functional units responsible for driving biological processes within cells. A faithful reconstruction of the ent…