259 citations · 631 across the 36 of their papers we have counts for
8 papers · 1 filter
Flexibility-Rigidity Index for Protein-Nucleic Acid Flexibility and Fluctuation Analysis
Kristopher Opron, Kelin Xia, Zachary F. Burton +1
Protein-nucleic acid complexes are important for many cellular processes including the most essential function such as transcription and translation. For many protein-nucleic acid…
Multiscale Gaussian network model (mGNM) and multiscale anisotropic network model (mANM)
Kelin Xia, Kristopher Opron, Guo-Wei Wei
Gaussian network model(GNM) and anisotropic network model(ANM) are some of the most popular methods for the study of protein flexibility and related functions. In this work, we pro…
A topological approach for protein classification
Zixuan Cang, Lin Mu, Kedi Wu +3
Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fund…
Finite Volume Formulation of the MIB Method for Elliptic Interface Problems
Yin Cao, Bao Wang, Kelin Xia +1
The matched interface and boundary (MIB) method has a proven ability for delivering the second order accuracy in handling elliptic interface problems with arbitrarily complex inter…
Capturing protein multiscale thermal fluctuations
Kristopher Opron, Kelin Xia, Guo-Wei Wei
Existing elastic network models are typically parametrized at a given cutoff distance and often fail to properly predict the thermal fluctuation of many macromolecules that involve…
Multiresolution topological simplification
Kelin Xia, Zhixiong Zhao, Guo-Wei Wei
Persistent homology has been devised as a promising tool for the topological simplification of complex data. However, it is computationally intractable for large data sets. In this…