75 citations · 115 across the 6 of their papers we have counts for
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Flexibility-Rigidity Index for Protein-Nucleic Acid Flexibility and Fluctuation Analysis
Kristopher Opron, Kelin Xia, Zachary F. Burton +1
Protein-nucleic acid complexes are important for many cellular processes including the most essential function such as transcription and translation. For many protein-nucleic acid…
Multiscale Gaussian network model (mGNM) and multiscale anisotropic network model (mANM)
Kelin Xia, Kristopher Opron, Guo-Wei Wei
Gaussian network model(GNM) and anisotropic network model(ANM) are some of the most popular methods for the study of protein flexibility and related functions. In this work, we pro…
A topological approach for protein classification
Zixuan Cang, Lin Mu, Kedi Wu +3
Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fund…
Capturing protein multiscale thermal fluctuations
Kristopher Opron, Kelin Xia, Guo-Wei Wei
Existing elastic network models are typically parametrized at a given cutoff distance and often fail to properly predict the thermal fluctuation of many macromolecules that involve…
Correlation function based Gaussian network models
Kelin Xia, Kristopher Opron, Guo-Wei Wei
Gaussian network model (GNM) is one of the most accurate and efficient methods for biomolecular flexibility analysis. However, the systematic generalization of the GNM has been elu…
Fast and Anisotropic Flexibility-Rigidity Index
Kristopher Opron, Kelin Xia, Guo-Wei Wei
The flexibility-rigidity index (FRI) is a newly proposed method for the construction of atomic rigidity functions. The FRI method analyzes protein rigidity and flexibility and is c…