246 citations · 543 across the 21 of their papers we have counts for
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q-bio.QM2013
Improved design and screening of high bioactivity peptides for drug discovery
Sébastien Giguère, François Laviolette, Mario Marchand +4
The discovery of peptides having high biological activity is very challenging mainly because there is an enormous diversity of compounds and only a minority have the desired proper…
q-bio.QM2012★ 42 cited
Learning a peptide-protein binding affinity predictor with kernel ridge regression
Sébastien Giguère, Mario Marchand, François Laviolette +2
We propose a specialized string kernel for small bio-molecules, peptides and pseudo-sequences of binding interfaces. The kernel incorporates physico-chemical properties of amino ac…