205 citations · 207 across the 4 of their papers we have counts for
4 papers
Decoding the mechanisms underlying cell-fate decision-making during stem cell differentiation by Random Circuit Perturbation
Bin Huang, Mingyang Lu, Madeline Galbraith +3
Stem cells can precisely and robustly undergo cellular differentiation and lineage commitment, referred to as stemness. However, how the gene network underlying stemness regulation…
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma
Fengdan Ye, Dongya Jia, Mingyang Lu +2
Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthes…
Distinguishing Mechanisms Underlying EMT Tristability
Dongya Jia, Mohit Kumar Jolly, Satyendra C. Tripathi +10
Background: The Epithelial-Mesenchymal Transition (EMT) endows epithelial-looking cells with enhanced migratory ability during embryonic development and tissue repair. EMT can also…
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
Mohit Kumar Jolly, Marcelo Boareto, Bin Huang +5
Understanding cell-fate decisions during tumorigenesis and metastasis is a major challenge in modern cancer biology. One canonical cell-fate decision that cancer cells undergo is E…