1 citations · 1 across the 2 of their papers we have counts for
4 papers
COBS: a Compact Bit-Sliced Signature Index
Timo Bingmann, Phelim Bradley, Florian Gauger +1
We present COBS, a COmpact Bit-sliced Signature index, which is a cross-over between an inverted index and Bloom filters. Our target application is to index -mers of DNA samples…
Identifying lineage effects when controlling for population structure improves power in bacterial association studies
Sarah G Earle, Chieh-Hsi Wu, Jane Charlesworth +16
Bacteria pose unique challenges for genome-wide association studies (GWAS) because of strong structuring into distinct strains and substantial linkage disequilibrium across the gen…
An integrative statistical model for inferring strain admixture within clinical Plasmodium falciparum isolates
John D. O'Brien, Zamin Iqbal, Lucas Amenga-Etego
Since the arrival of genetic typing methods in the late 1960's, researchers have puzzled at the clinical consequence of observed strain mixtures within clinical isolates of Plasmod…
A Bayesian approach to inferring the phylogenetic structure of communities from metagenomic data
John O'Brien, Xavier Didelot, Zamin Iqbal +3
Metagenomics provides a powerful new tool set for investigating evolutionary interactions with the environment. However, an absence of model-based statistical methods means that re…