134 citations · 360 across the 8 of their papers we have counts for
4 papers · 1 filter
Entropic contribution to phenotype fitness
Pablo Catalán, Juan Antonio García-Martín, Jacobo Aguirre +2
All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in…
From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
Susanna Manrubia, José A. Cuesta, Jacobo Aguirre +15
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to t…
On the networked architecture of genotype spaces and its critical effects on molecular evolution
Jacobo Aguirre, Pablo Catalán, José A. Cuesta +1
Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inhe…
The struggle for space: Viral extinction through competition for cells
Jose A. Cuesta, Jacobo Aguirre, Jose A. Capitan +1
The design of protocols to suppress the propagation of viral infections is an enduring enterprise, especially hindered by limited knowledge of the mechanisms through which extincti…