4 papers
Gain of Entrainment in Nonlinear Cascades
Ram Massas, Michael Margaliot
We consider the gain of entrainment (GOE)--the difference between the average steady-state output under a periodic input and the steady-state output under a constant input with the…
On the Cost of Entrainment in Protein Translation
Ram Massas, Michael Margaliot
Biological systems often synchronize their dynamics with periodic environmental and intracellular signals. Whether such periodic coordination can also improve performance, however,…
A universal multi-turnpike principle for optimal allocation of translational resources
Ram Massas, Thomas Kriecherbauer, Lars Grüne +2
mRNA translation in the cell requires efficient allocation of shared and limited resources including free ribosomes, tRNA molecules, and initiation factors across multiple transcri…
On the gain of entrainment in stable linear control systems with a nonlinear output
Ram Massas, Michael Margaliot
A control system admits a positive gain of entrainment (GOE) if entrainment to a periodic input yields a larger output, on average, than the output generated by the corresponding c…