2 papers
math.AP2019
From individual-based mechanical models of multicellular systems to free-boundary problems
Tommaso Lorenzi, Philip J. Murray, Mariya Ptashnyk
In this paper we present an individual-based mechanical model that describes the dynamics of two contiguous cell populations with different proliferative and mechanical characteris…
q-bio.TO2015
Multiscale modelling of intestinal crypt organization and carcinogenesis
Alexander G. Fletcher, Philip J. Murray, Philip K. Maini
Colorectal cancers are the third most common type of cancer. They originate from intestinal crypts, glands that descend from the intestinal lumen into the underlying connective tis…