3 papers
q-bio.PE2024
Population dynamics of multiple ecDNA types
Elisa Scanu, Benjamin Werner, Weini Huang
Extrachromosomal DNA (ecDNA) can drive oncogene amplification, gene expression and intratumor heterogeneity, representing a major force in cancer initiation and progression. The ph…
q-bio.PE2023
Single-cell mutational burden distributions in birth-death processes
Christo Morison, Dudley Stark, Weini Huang
Genetic mutations are footprints of tumour growth. While mutation data in bulk samples has been used to infer evolutionary parameters hard to measure in vivo, the advent of single-…
q-bio.PE2015
Stochastic evolutionary games in dynamic populations
Weini Huang, Christoph Hauert, Arne Traulsen
Frequency dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency dependent selection, the average fitness o…