204 citations · 204 across the 6 of their papers we have counts for
6 papers
Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA
Jack W Shepherd, Sebastien Guilbaud, Zhaokun Zhou +7
Biopolymer topology is critical for determining interactions inside cell environments, exemplified by DNA where its response to mechanical perturbation is as important as biochemic…
Single-molecule techniques in biophysics: a review of the progress in methods and applications
Helen Miller, Zhaokun Zhou, Jack Shepherd +2
Single-molecule biophysics has transformed our understanding of the fundamental molecular processes involved in living biological systems, but also of the fascinating physics of li…
Force spectroscopy in studying infection
Zhaokun Zhou, Mark C. Leake
Biophysical force spectroscopy tools - for example optical tweezers, magnetic tweezers, atomic force microscopy, - have been used to study elastic, mechanical, conformational and d…
Developing a new biophysical tool to combine magneto-optical tweezers with super-resolution fluorescence microscopy
Zhaokun Zhou, Helen Miller, Adam J. M. Wollman +1
We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse config…
Probing DNA interactions with proteins using a single-molecule toolbox: inside the cell, in a test tube, and in a computer
Adam J. M. Wollman, Helen Miller, Zhaokun Zhou +1
DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function.…
Superresolution imaging of single DNA molecules using stochastic photoblinking of minor groove and intercalating dyes
Helen Miller, Zhaokun Zhou, Adam J. M. Wollman +1
As proof-of-principle for generating superresolution structural information from DNA we applied a method of localization microscopy utilizing photoblinking comparing intercalating…