52 citations · 72 across the 7 of their papers we have counts for
9 papers
Intuitive dissection of the Gaussian information bottleneck method with an application to optimal prediction
Vahe Galstyan, Age Tjalma, Pieter Rein ten Wolde
Efficient signal representation is essential for the functioning of living and artificial systems operating under resource constraints. A widely recognized framework for deriving s…
Trade-offs between cost and information in cellular prediction
Age J. Tjalma, Vahe Galstyan, Jeroen Goedhart +3
Living cells can leverage correlations in environmental fluctuations to predict the future environment and mount a response ahead of time. To this end, cells need to encode the pas…
Modeling and mechanical perturbations reveal how spatially regulated anchorage gives rise to spatially distinct mechanics across the mammalian spindle
Pooja Suresh, Vahe Galstyan, Rob Phillips +1
During cell division, the spindle generates force to move chromosomes. In mammals, microtubule bundles called kinetochore-fibers (k-fibers) attach to and segregate chromosomes. To…
Allostery and Kinetic Proofreading
Vahe Galstyan, Rob Phillips
Kinetic proofreading is an error correction mechanism present in the processes of the central dogma and beyond, and typically requires the free energy of nucleotide hydrolysis for…
Proofreading through spatial gradients
Vahe Galstyan, Kabir Husain, Fangzhou Xiao +2
Key enzymatic processes in biology use the nonequilibrium error correction mechanism called kinetic proofreading to enhance their specificity. Kinetic proofreading typically requir…
Combinatorial Control through Allostery
Vahe Galstyan, Luke Funk, Tal Einav +1
Many instances of cellular signaling and transcriptional regulation involve switch-like molecular responses to the presence or absence of input ligands. To understand how these res…
A note on the breathing mode of an elastic sphere in Newtonian and complex fluids
Vahe Galstyan, On Shun Pak, Howard A. Stone
Experiments on the acoustic vibrations of elastic nanostructures in fluid media have been used to study the mechanical properties of materials, as well as for mechanical and biolog…
Stochastic Total Quasi-Steady-State Approximation for the Michaelis-Menten Scheme
Vahe Galstyan
In biochemical systems the Michaelis-Menten (MM) scheme is one of the best-known models of the enzyme- catalyzed kinetics. In the academic literature the MM approximation has been…
Dynamics of the Chemical Master Equation, a strip of chains of equations in d-dimensional space
Vahe Galstyan, David B. Saakian
We investigate the multi-chain version of the Chemical Master Equation, when there are transitions between different states inside the long chains, as well as transitions between (…