126 citations · 612 across the 28 of their papers we have counts for
4 papers · 1 filter
Structurally constrained protein evolution: results from a lattice simulation
Ugo Bastolla, Michele Vendruscolo, H. Eduardo Roman
We simulate the evolution of a protein-like sequence subject to point mutations, imposing conservation of the ground state, thermodynamic stability and fast folding. Our model is a…
Neutral evolution of model proteins: diffusion in sequence space and overdispersion
Ugo Bastolla, H. Eduardo Roman, Michele Vendruscolo
We simulate the evolution of model protein sequences subject to mutations. A mutation is considered neutral if it conserves 1) the structure of the ground state, 2) its thermodynam…
Testing a new Monte Carlo Algorithm for Protein Folding
Ugo Bastolla, Helge Frauenkron, Erwin Gerstner +2
We demonstrate that the recently proposed pruned-enriched Rosenbluth method PERM (P. Grassberger, Phys. Rev. E, in press (1997)) leads to extremely efficient algorithms for the fol…
Phase Transitions of Single Semi-stiff Polymer Chains
Ugo Bastolla, Peter Grassberger
We study numerically a lattice model of semiflexible homopolymers with nearest neighbor attraction and energetic preference for straight joints between bonded monomers. For this we…