79 citations · 295 across the 7 of their papers we have counts for
7 papers
Charge and hydration structure of dendritic polyelectrolytes: molecular simulations of polyglycerol sulphate
Rohit Nikam, Xiao Xu, Matthias Ballauff +2
Macromolecules based on dendritic or hyperbranched polyelectrolytes have been emerging as high potential candidates for biomedical applications. Here we study the charge and solvat…
Competitive sorption of mono- versus di-valent ions by highly charged globular macromolecules
Rohit Nikam, Xiao Xu, Matej Kanduč +1
When a highly charged globular macromolecule, such as a dendritic polyelectrolyte or charged nanogel, is immersed into a physiological electrolyte solution, monovalent and divalent…
Interaction of Proteins with Polyelectrolytes: A Comparison between Theory and Experiment
Xiao Xu, Stefano Angioletti-Uberti, Yan Lu +2
We discuss recent investigations of the interaction of polyelectrolytes with proteins. In particular, we review our recent studies on the interaction of simple proteins such as hum…
Counterion-release entropy governs the inhibition of serum proteins by polyelectrolyte drugs
Xiao Xu, Qidi Ran, Pradip Dey +4
Dendritic polyelectrolytes constitute high potential drugs and carrier systems for biomedical purposes, still their biomolecular interaction modes, in particular those determining…
Charged dendrimers revisited: Effective charge and surface potential of dendritic polyglycerol sulfate
Xiao Xu, Qidi Ran, Rainer Haag +2
We investigate key electrostatic features of charged dendrimers at hand of the biomedically important dendritic polyglycerol sulfate (dPGS) macromolecule using multi-scale computer…
Potential of mean force and transient states in polyelectrolyte complexation
Xiao Xu, Matej Kanduč, Jianzhong Wu +1
The association between polyelectrolytes (PEs) of the same size but opposite charge is systematically studied in terms of the potential of mean force (PMF) along their center-of-ma…
Interaction of Human Serum Albumin with short Polyelectrolytes: A study by Calorimetry and Computer Simulation
Shun Yu, Xiao Xu, Cemil Yigit +5
We present a comprehensive study of the interaction of human serum albumin (HSA) with poly(acrylic acid) (PAA; number average degree of polymerization: 25) in aqueous solution. The…