1.3k citations · 1.6k across the 7 of their papers we have counts for
7 papers
Modeling microscopic swimmers at low Reynolds number
David J. Earl, C. M. Pooley, J. F. Ryder +2
We employ three numerical methods to explore the motion of low Reynolds number swimmers, modeling the hydrodynamic interactions by means of the Oseen tensor approximation, lattice…
Parallel Tempering: Theory, Applications, and New Perspectives
David J. Earl, Michael W. Deem
We review the history of the parallel tempering simulation method. From its origins in data analysis, the parallel tempering method has become a standard workhorse of physiochemica…
Glassy Dynamics in the Adaptive Immune Response Prevents Autoimmune Disease
Jun Sun, David J. Earl, Michael W. Deem
The immune system normally protects the human host against death by infection. However, when an immune response is mistakenly directed at self antigens, autoimmune disease can occu…
Quantifying Influenza Vaccine Efficacy and Antigenic Distance
Vishal Gupta, David J. Earl, Michael W. Deem
We introduce a new measure of antigenic distance between influenza A vaccine and circulating strains. The measure correlates well with efficacies of the H3N2 influenza A component…
Markov Chains of Infinite Order and Asymptotic Satisfaction of Balance: Application to the Adaptive Integration Method
David J. Earl, Michael W. Deem
Adaptive Monte Carlo methods can be viewed as implementations of Markov chains with infinite memory. We derive a general condition for the convergence of a Monte Carlo method whose…
Evolvability is a Selectable Trait
David J. Earl, Michael W. Deem
Concomitant with the evolution of biological diversity must have been the evolution of mechanisms that facilitate evolution, due to the essentially infinite complexity of protein s…