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q-bio.BM2005
Study the effects of metallic ions on the combination of DNA and histones with molecular combing technique
Yu-Ying Liu, Peng-Ye Wang, Shuo-Xing Dou +3
The effects of monovalent (Na+, K+) and divalent (Mg2+, Ca2+, Mn2+) ions on the interaction between DNA and histone are studied using the molecular combing technique. Lamda-DNA mol…
q-bio.BM2003
Ionic effect on combing of single DNA molecules and observation of their force-induced melting by fluorescence microscopy
Yu-Ying Liu, Peng-Ye Wang, Shuo-Xing Dou +4
Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, we observed that the length…