5 papers
Automated stereotactic radiosurgery planning using a human-in-the-loop reasoning large language model agent
Humza Nusrat, Luke Francisco, Bing Luo +10
Stereotactic radiosurgery (SRS) demands precise dose shaping around critical structures, yet black-box AI systems have limited clinical adoption due to opacity concerns. We tested…
When AI Does Science: Evaluating the Autonomous AI Scientist KOSMOS in Radiation Biology
Humza Nusrat, Omar Nusrat
Agentic AI "scientists" now use language models to search the literature, run analyses, and generate hypotheses. We evaluate KOSMOS, an autonomous AI scientist, on three problems i…
Development and pilot evaluation of a virtual reality simulator for HDR prostate brachytherapy
Anton Varlukhin, Mackenzie Smith, Fahad Alam +8
Purpose: To develop a virtual reality simulator for high dose rate prostate brachytherapy and to test whether participation is associated with immediate gains in self-reported conf…
Characterization and ex vivo application of flexible 2D scintillating coatings in ultra-high dose rate electron beams for FLASH radiotherapy
Verdi Vanreusel, Stephen Brown, Shujat Ali +11
The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains…
Autonomous Radiotherapy Treatment Planning Using DOLA: A Privacy-Preserving, LLM-Based Optimization Agent
Humza Nusrat, Bing Luo, Ryan Hall +5
Radiotherapy treatment planning is a complex and time-intensive process, often impacted by inter-planner variability and subjective decision-making. To address these challenges, we…