3 papers
physics.bio-ph2025
Nonlocal decoding of positional and correlational information during development
Alex Chen Yi Zhang, Pablo Mateu Hoyos, David Brückner +1
In many developmental systems, cells differentiate into a tissue by reading out morphogen concentration fields, a process fundamentally limited by noise. How much can the precision…
physics.bio-ph2025
Marr's three levels for embryonic development: information, dynamical systems, gene networks
David B. Brückner, GaÅ¡per TkaÄik
Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge au…
q-bio.MN2025
Invariant non-equilibrium dynamics of transcriptional regulation optimize information flow
Benjamin Zoller, Alexis Bénichou, Thomas Gregor +1
Eukaryotic gene regulation is based on stochastic yet controlled promoter switching, during which genes transition between transcriptionally active and inactive states. Despite the…