5 citations · 9 across the 3 of their papers we have counts for
3 papers
A Review of EMA Public Assessment Reports where Non-Proportional Hazards were Identified
Florian Klinglmueller, Norbert Benda, Tim Friede +8
While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best approach under non-proportiona…
Online control of the False Discovery Rate in group-sequential platform trials
Sonja Zehetmayer, Martin Posch, Franz Koenig
When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate (FDR) assume that…
Adaptive Survival Trials
Dominic Magirr, Thomas Jaki, Franz Koenig +1
Mid-study design modifications are becoming increasingly accepted in confirmatory clinical trials, so long as appropriate methods are applied such that error rates are controlled.…