2 papers
stat.ME2025
Is Repeated Bayesian Interim Analysis Consequence-Free?
Suyu Liu, Beibei Guo, Laura Thompson +2
Interim analyses are vital in clinical trials for early decision-making. While frequentist implications are well-established, the consequences of repeated Bayesian interim monitori…
stat.ME2025
ROSE: Randomized Optimal Selection Design for Dose Optimization
Shuqi Wang, Ying Yuan, Suyu Liu
The U.S. Food and Drug Administration (FDA) launched Project Optimus to shift the objective of dose selection from the maximum tolerated dose to the optimal biological dose (OBD),…