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math.OC2024
A new approach to data assimilation initialization problems with sparse data using multiple cost functions
David J. Abers, George Hripcsak, Lena Mamykina +2
This article develops a novel data assimilation methodology, addressing challenges that are common in real-world settings, such as severe sparsity of observations, lack of reliable…
math.OC2024
A Stochastic Model-Based Control Methodology for Glycemic Management in the Intensive Care Unit
Melike Sirlanci, George Hripcsak, Cecilia C. Low Wang +5
Intensive care unit (ICU) patients exhibit erratic blood glucose (BG) fluctuations, including hypoglycemic and hyperglycemic episodes, and require exogenous insulin delivery to kee…