5 papers
Digital Twin AI: Opportunities and Challenges from Large Language Models to World Models
Rong Zhou, Dongping Chen, Zihan Jia +24
Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration o…
PDA in Action: Ten Principles for High-Quality Multi-Site Clinical Evidence Generation
Yong Chen, Jiayi Tong, Yiwen Lu +13
Background: Distributed Research Networks (DRNs) offer significant opportunities for collaborative multi-site research and have significantly advanced healthcare research based on…
Empowering Clinical Trial Design through AI: A Randomized Evaluation of PowerGPT
Yiwen Lu, Lu Li, Dazheng Zhang +20
Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many…
OrigamiPlot: An R Package and Shiny Web App Enhanced Visualizations for Multivariate Data
Yiwen Lu, Jiayi Tong, Yuqing Lei +8
We introduce OrigamiPlot, an open-source R package and Shiny web application designed to enhance the visualization of multivariate data. This package implements the origami plot, a…
Zodiac: A Cardiologist-Level LLM Framework for Multi-Agent Diagnostics
Yuan Zhou, Peng Zhang, Mengya Song +5
Large language models (LLMs) have demonstrated remarkable progress in healthcare. However, a significant gap remains regarding LLMs' professionalism in domain-specific clinical pra…