28 citations · 29 across the 3 of their papers we have counts for
3 papers
q-bio.BM2005★ 1 cited
Design of HIV-1-PR inhibitors which do not create resistance: blocking the folding of single monomers
R. A. Broglia, G. Tiana, L. Sutto +2
One of the main problems of drug design is that of optimizing the drug--target interaction. In the case in which the target is a viral protein displaying a high mutation rate, a se…
q-bio.BM2004★ 28 cited
Thermodynamics of beta-amyloid fibril formation
G. Tiana, F. Simona, R. A. Broglia +1
Amyloid fibers are aggregates of proteins. They are built out of a peptide called --amyloid (A) containing between 41 and 43 residues, produced by the action of an enzyme whi…
cond-mat.soft2003
Understanding the determinants of stability and folding of small globular proteins from their energetics
G. Tiana, F. Simona, G. M. S. De Mori +2
The results of minimal model calculations suggest that the stability and the kinetic accessibility of the native state of small globular proteins are controlled by few "hot" sites.…