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cond-mat.soft2002★ 14 cited
Resistance proof, folding-inhibitor drugs
R. Broglia, G. Tiana, R. Berera
Conventional drugs work, as a rule, by inhibiting the enzymatic activity of specific proteins, capping their active site. In this paper we present a model of non- conventional drug…
cond-mat.soft2002
Design and Folding of Dimeric Proteins
G. Tiana, R. A. Broglia
In a similar way in which the folding of single--domain proteins provide an important test in the study of self--organization, the folding of homodimers constitute a basic challeng…