4 papers
Allostery Beyond Amplification: Temporal Regulation of Signaling Information
Pedro Pessoa, Steve Pressé, S. Banu Ozkan
Allostery is a fundamental mechanism of protein regulation and is commonly interpreted as modulating enzymatic activity or product abundance. Here we show that this view is incompl…
Inherited or produced? Inferring protein production kinetics when protein counts are shaped by a cell's division history
Pedro Pessoa, Juan Andres Martinez, Vincent Vandenbroucke +2
Inferring protein production kinetics for dividing cells is complicated due to protein inheritance from the mother cell. For instance, fluorescence measurements -- commonly used to…
Mamba time series forecasting with uncertainty quantification
Pedro Pessoa, Paul Campitelli, Douglas P. Shepherd +2
State space models, such as Mamba, have recently garnered attention in time series forecasting due to their ability to capture sequence patterns. However, in electricity consumptio…
Avoiding subtraction and division of stochastic signals using normalizing flows: NFdeconvolve
Pedro Pessoa, Max Schweiger, Lance W. Q. Xu +4
Across the scientific realm, we find ourselves subtracting or dividing stochastic signals. For instance, consider a stochastic realization, , generated from the addition or mult…