316 citations · 2.3k across the 42 of their papers we have counts for
Showing 2010Show all
2 papers · 1 filter
cond-mat.stat-mech2010★ 211 cited
The geometry of nonlinear least squares with applications to sloppy models and optimization
Mark K. Transtrum, Benjamin B. Machta, James P. Sethna
Parameter estimation by nonlinear least squares minimization is a common problem with an elegant geometric interpretation: the possible parameter values of a model induce a manifol…
q-bio.SC2010★ 190 cited
A minimal model of plasma membrane heterogeneity requires coupling cortical actin to criticality
Benjamin B. Machta, Stefanos Papanikolaou, James P. Sethna +1
We present a minimal model of plasma membrane heterogeneity that combines criticality with connectivity to cortical cytoskeleton. Our model is motivated by recent observations of m…