2 papers
q-bio.QM2026
Identifying expanding TCR clonotypes with a longitudinal Bayesian mixture model and their associations with cancer patient prognosis, metastasis-directed therapy, and VJ gene enrichment
David Swanson, Alexander Sherry, Cara Haymaker +2
Examination of T-cell receptor (TCR) clonality has become a way of understanding immunologic response to cancer and its interventions in recent years. An aspect of these analyses i…
stat.ME2025
Variance component mixture modelling for longitudinal T-cell receptor clonal dynamics
David Swanson, Alexander Sherry, Chad Tang
Studies of T cells and their clonally unique receptors have shown promise in elucidating the association between immune response and human disease. Methods to identify T-cell recep…