2 papers
physics.bio-ph2026
Optimal Discretization in Hour-Glass Molecular Clocks Driven by Oscillating Free Energy
Zhuangcheng Zhen, Kaiyue Shi, Qi Ouyang +1
Hour-glass clocks do not free-run; they keep time by riding an external rhythm. Motivated by the primordial KaiBC system in cyanobacteria, we study a driven, finite-state molecular…
q-bio.NC2026
Irreversible behavior drives neural flows in the hippocampus
Kaiyue Shi, Christopher W. Lynn
In the brain, neural activity undergoes directed flows between states, thus breaking time-reversal symmetry. At the same time, animals also exhibit irreversible flows between behav…